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1

PRODUCTION OF HUMAN THERAPEUTIC PROTEINS IN TRANSGENIC ANIMALS

LEON W. HOYER, WILLIAM N. DROHAN, HENRYK LUBON

Journal:

Année:

1994

Langue:

english

Fichier:

PDF, 251 KB

english, 1994

2

Transgenic pigs as bioreactors: a comparison of gamma-carboxylation of glutamic acid in recombinant human protein C and factor IX by the mammary gland

Kevin E Van Cott, Stephen P Butler, Christopher G Russell, Anu Subramanian, Henryk Lubon, F.C Gwazdauskas, James Knight, William N Drohan, William H Velander

Journal:

Genetic Analysis: Biomolecular Engineering

Année:

1999

Langue:

english

Fichier:

PDF, 87 KB

english, 1999

3

Affinity purification of biologically active and inactive forms of recombinant human protein C produced in porcine mammary gland

Kevin E. van Cott, Barry Williams, William H. Velander, Frank Gwazdauskas, Tim Lee, Henryk Lubon, William N. Drohan

Journal:

Journal of Molecular Recognition

Année:

1996

Langue:

english

Fichier:

PDF, 872 KB

english, 1996

4

Erratum

Rekha K. Paleyanda, Da-Wei Zhang, Lothar Hennighausen, Robert A. Mcknight, Henryk Lubon

Journal:

Transgenic Research

Année:

1995

Fichier:

PDF, 105 KB

1995

5

Inefficient processing of human protein C in the mouse mammary gland

William N. Drohan, Da-Wei Zhang, Rekhak Paleyanda, Rouling Chang, Marie Wroble, William Velander, Henryk Lubon

Journal:

Transgenic Research

Année:

1994

Langue:

english

Fichier:

PDF, 2.09 MB

english, 1994

6

Regulation of human protein C gene expression by the mouse WAP promoter

Rekha K. Paleyanda, Da-Wei Zhang, Lothar Hennighausen, Robert A. McKnight, Henryk Lubon

Journal:

Transgenic Research

Année:

1994

Langue:

english

Fichier:

PDF, 4.80 MB

english, 1994

7

Aqueous two-phase partitioning of milk proteins

Kenneth D. Cole, Timothy K. Lee, Henryk Lubon

Journal:

Applied Biochemistry and Biotechnology

Année:

1997

Langue:

english

Fichier:

PDF, 1.67 MB

english, 1997

8

Secretion of recombinant human fibrinogen by the murine mammary gland

Stephen Butler, Tanya O'Sickey, Susan Lord, Henryk Lubon, Francis Gwazdauskas, William Velander

Journal:

Transgenic Research

Année:

2004

Langue:

english

Fichier:

PDF, 294 KB

english, 2004

9

A transgenic compendium engineered

Journal:

Nature Biotechnology

Année:

1997

Fichier:

PDF, 321 KB

1997

10

Transgenic pigs produce functional human factor VIII in milk

Paleyanda, Rekha K., Velander, William H., Lee, Timothy K., Scandella, Dorothea H., Gwazdauskas, Francis C., Knight, James W., Hoyer, Leon W., Drohan, William N., Lubon, Henryk

Journal:

Nature Biotechnology

Année:

1997

Fichier:

PDF, 669 KB

1997

11

Transgenic Livestock as Drug Factories

Velander, William H., Lubon, Henryk, Drohan, William N.

Journal:

Scientific American

Année:

1997

Langue:

english

Fichier:

PDF, 429 KB

english, 1997

12

Recombinant Human Protein C Expression in the Milk of Transgenic Pigs and the Effect on Endogenous Milk Immunoglobulin and Transferrin Levels

Kevin E. Van Cott, Henryk Lubon, F.C. Gwazdauskas, James Knight, William N. Drohan, William H. Velander

Journal:

Transgenic Research

Année:

2001

Langue:

english

Fichier:

PDF, 77 KB

english, 2001

13

Commentary on Houdebine's review

Henryk Lubon, Carol Palmer

Journal:

Transgenic Research

Année:

2000

Langue:

english

Fichier:

PDF, 36 KB

english, 2000

14

Phenotypic and genotypic stability of multiple lines of transgenic pigs expressing recombinant human protein C

Kevin E. Van Cott, Henryk Lubon, Christopher G. Russell, Stephen P. Butler, F.C. Gwazdauskas, James Knight, William N. Drohan, William H. Velander

Journal:

Transgenic Research

Année:

1997

Langue:

english

Fichier:

PDF, 1.93 MB

english, 1997

15

Genetic variants of chicken erythrocyte histone H5

Ewa Górnicka-Michalska, Jan Pałyga, Henryk Lubon, Andrzej Kowalski, Katarzyna Cywa-Benko

Journal:

Année:

1998

Langue:

english

Fichier:

PDF, 770 KB

english, 1998

16

Changes in liver nuclear sap proteins during chick embryo development

Jan Palyga, Henryk Luboń, Danuta Tyrawska-Spychalowa

Journal:

Development Genes and Evolution

Année:

1984

Langue:

english

Fichier:

PDF, 626 KB

english, 1984

17

Interactions between cellular regulatory proteins and a unique sequence region in the human cytomegalovirus major immediate-early promoter

Peter Ghazal, Henryk Lubon, Catherine Reynolds-Kohler, Lothar Hennighausen, Jay A. Nelson

Journal:

Année:

1990

Langue:

english

Fichier:

PDF, 3.97 MB

english, 1990

18

Blood proteins from transgenic animal bioreactors

Henryk Luboń, Rekha K. Paleyanda, William H. Velander, William N. Drohan

Journal:

Transfusion Medicine Reviews

Année:

1996

Langue:

english

Fichier:

PDF, 1.11 MB

english, 1996

19

In vitro transcription of the mouse whey acidic protein promoter is affected by upstream sequences

Henryk Lubon, Christoph W. Pittius, Lothar Hennighausen

Journal:

Année:

1989

Langue:

english

Fichier:

PDF, 451 KB

english, 1989

20

The Use of the Uromodulin Promoter to Target Production of Recombinant Proteins into Urine of Transgenic Animals

Halina M. Zbikowska, Nadia Soukhareva, Reza Behnam, Rosemary Chang, Roman Drews, Henryk Lubon, David Hammond, Serguei Soukharev

Journal:

Transgenic Research

Année:

2002

Langue:

english

Fichier:

PDF, 325 KB

english, 2002

21

The Porcine Mammary Gland as a Bioreactor for Complex Proteinsa

TÜLIN MORCÖL, ROBERT M. AKERS, JOHN L. JOHNSON, BARRY L. WILLIAMS, FRANCIS C. GWAZDAUSKAS, JAMES W. KNIGHT, HENRYK LUBON, REKHA K. PALEYANDA, WILLIAM N. DROHAN, WILLIAM H. VELANDER

Journal:

Annals of the New York Academy of Sciences

Année:

1994

Langue:

english

Fichier:

PDF, 1.68 MB

english, 1994

22

Rate Limitations in Posttranslational Processing by the Mammary Gland of Transgenic Animals

ANURADHA SUBRAMANIAN, REKHA K. PALEYANDA, HENRYK LUBON, BARRY L. WILLIAMS, FRANCIS C. GWAZDAUSKAS, JAMES W. KNIGHT, WILLIAM N. DROHAN, WILLIAM H. VELANDER

Journal:

Annals of the New York Academy of Sciences

Année:

1996

Langue:

english

Fichier:

PDF, 523 KB

english, 1996

23

[Biotechnology Annual Review] Biotechnolgy Annual Review Volume 4 || Transgenic animal bioreactors in biotechnology and production of blood proteins

Année:

1998

Langue:

english

Fichier:

PDF, 3.86 MB

english, 1998

24

Binding of Transcription Factors and Creation of a Large Nucleoprotein Complex on the Human Cytomegalovirus Enhancer

Peter Ghazal, Henryk Lubon, Bernhard Fleckenstein and Lothar Hennighausen

Journal:

Proceedings of the National Academy of Sciences

Année:

1987

Langue:

english

Fichier:

PDF, 1.27 MB

english, 1987

25

Cell-Specific Activity of the Human Immunodeficiency Virus Enhancer Repeat In Vitro

LUBON, HENRYK, GHAZAL, PETER, NELSON, JAY A., HENNIGHAUSEN, LOTHAR

Journal:

AIDS Research and Human Retroviruses

Année:

1988

Langue:

english

Fichier:

PDF, 8.13 MB

english, 1988

26

Nuclear proteins form lactating mammary glands bind to the promoter of a milk protein gene

Lubon, Henryk, Hennighausen, Lothar

Journal:

Nucleic Acids Research

Année:

1987

Langue:

english

Fichier:

PDF, 1.19 MB

english, 1987

27

Proteolytic Maturation of Protein C Upon Engineering the Mouse Mammary Gland to Express Furin

Roman Drews, Rekha K. Paleyanda, Timothy K. Lee, Rouling R. Chang, Alnawaz Rehemtulla, Randal J. Kaufman, William N. Drohan and Henryk Lubon

Journal:

Proceedings of the National Academy of Sciences

Année:

1995

Langue:

english

Fichier:

PDF, 1.10 MB

english, 1995

28

Uromodulin promoter directs high-level expression of biologically active human α1-antitrypsin into mouse urine

ZBIKOWSKA, Halina M., SOUKHAREVA, Nadia, BEHNAM, Reza, LUBON, Henryk, HAMMOND, David, SOUKHAREV, Serguei

Journal:

Biochemical Journal

Année:

2002

Langue:

english

Fichier:

PDF, 152 KB

english, 2002

29

Proteolytic Processing of Human Protein C in Swine Mammary Gland

Lee, Timothy K., Drohan, William N., Lubon, Henryk

Journal:

Journal of Biochemistry

Année:

1995

Langue:

english

Fichier:

PDF, 3.25 MB

english, 1995

30

Production of human therapeutic proteins in transgenic animals

Hoyer, Leon W., Drohan, William N, Henryk, Lubon

Journal:

Année:

1994

Fichier:

PDF, 292 KB

1994